I don't doubt that it can be done at USC, but I disagree that one coach can do it. From watching Clemson build a program over the last 10 years, to me its obvious that you need buy in and support from the top to the bottom.
At Clemson from the President and BOT to the AD, students, alumni, to the guys on the janitorial staff at the football facility, everyone is on the same page and pulling in the same direction. It also takes making unpopular and or tough decisions. Until that happens, to quote the OBC, "It is, what it is".
USC is in a top conference, is bringing in plenty of cash, and has a loyal fan base, alumni with big $$, so what is missing? I think it is dedication from the upper echelons of the university. Is the BOT and President dedicated to becoming a premier football program? If not then it will never happen. I think the BOT went the easy route when they promoted Ray Tanner to be AD and demonstrates their commitment level to their athletic programs. RT is heck of a nice guy and legendary baseball coach, but under qualified to be the AD at school the size of USC. He's out of his depth. How many other D1 schools would have made that move? I cant think of one that internally promoted a head coach to AD in D1. Im sure it happens and D2 and D3 schools but I can't recall it happening anywhere else.
There are other things at a university that are important, but we all know that football makes all the $$ and allows all the other sports to exist. The championships in non-revenue sports are great but they are secondary to the cash cow that is college football in the south. I would bet that 80K in the stands for 7 games a year is more butts in seats than all the other sports combined, if not its probably pretty close. It drives other things like student enrollment and gives a university national exposure that it wouldn't otherwise have.